Taking an Antidepressant But Still Experiencing Depression?
If you're taking an antidepressant but still experiencing depression symptoms, you may qualify for a clinical research study evaluating an investigational add-on treatment for Major Depressive Disorder (MDD).
Led by Dr. Walid Talat Aziz, MD · Double Board-Certified Psychiatrist
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Answer 5 quick questions. Our team will follow up with a short call to complete the full screening. No commitment required.
Step 1 of 2 · Screening questions

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Dr. Walid Talat Aziz, MD
Principal Investigator
Double Board-Certified Psychiatrist
Denali Health Plant CityStudy leadership
About Dr. Walid Talat Aziz, MD
Principal Investigator · Double Board-Certified Psychiatrist
Dr. Aziz leads clinical mental health care, guiding you from your initial evaluation through every step of your treatment plan.
Patient-Centered Clinical Guidance
- Reviews your diagnosis, symptoms, and medication history with you
- Answers every question about your treatment options before you decide anything
- Oversees your safety and care for the full length of your treatment
- Double Board-CertifiedPsychiatrist
- Principal InvestigatorDenali Health Plant City
- Comprehensive CareInitial evaluation through full treatment
“Depression accompanied by insomnia and anxiety can feel overwhelming. Our research aims to find treatments that address these interconnected symptoms more effectively, while putting patient comfort and safety first.”
This is an investigational treatment being studied. Participation is voluntary. There is no guarantee of therapeutic benefit. Please consult with your doctor about all treatment options.
About This Depression Study
Who Can Participate?
Adults aged 18–75 diagnosed with Major Depressive Disorder who are still experiencing symptoms despite taking an antidepressant for at least 6 weeks.
What Is Being Studied?
An investigational add-on treatment for depression, compared with placebo, while participants continue their current antidepressant medication.
What Happens During the Study?
The study lasts approximately 20 weeks and includes weekly injections, regular study visits, and safety follow-up assessments.
Could This Study Help You?
You may be eligible to participate if you:
01
Age Requirement
Adults aged 18 to 75 years.
02
Have Major Depressive Disorder
You have been diagnosed with depression and are currently experiencing symptoms.
03
Are Taking an Antidepressant
You have been taking one qualifying antidepressant medication at a stable dose for at least 6 weeks.
04
Still Experience Depression Symptoms
Your current antidepressant has helped somewhat, but you continue to experience symptoms.
Other eligibility requirements apply. The study team will determine whether you qualify.
Participant support
Study Benefits & Details
What you receive as a participant in the RENEW clinical research study.
Compensation Per Visit
Compensation may be provided for completed study visits to cover your time and commitment. Specific amounts will be verified and reviewed with you by the study team.
Travel & Meal Reimbursement
Travel and meal reimbursement options may be available to help support your visits. Details will be verified with the study team during your initial visit.
Study-Related Care at No Cost
All study-related investigational treatment, doctor visits, health monitoring, and laboratory assessments are provided at no cost to you. No insurance is required.
Regular Clinic Visits
Visits occur approximately every 2 weeks during the treatment period, with ongoing safety monitoring, symptom assessments, and dedicated support from the research team.
Participation is voluntary. You may withdraw at any time. There is no guarantee of therapeutic benefit. Please consult with your doctor about all treatment options.
Questions & Answers
Frequently Asked Questions
Find answers to common questions about participating in the RENEW clinical research study.
Yes. This study is intended for adults aged 18–75 diagnosed with Major Depressive Disorder (MDD) who are currently experiencing depression symptoms.
Still have questions? We're here to help.
Request Your Free Evaluation
Find out if you're a good fit for this investigational study. Our team will contact you within 24 hours.

Why Request Today?
Voluntary Participation
We can only accept a limited number of participants for this investigational study.
No-Cost Evaluation
Your consultation and all study-related care is provided at no cost to qualified participants.
No Obligation
The consultation is informational only - you decide if this investigational study is right for you.
Get Help Today
Complete this quick form to see if you may qualify
Ready to learn more about this study?
Your information is secure and will never be shared with third parties
Contact the research site
Take the First Step Today
Call or text (813) 796-6716 or email info@denali-health.com.
Office location
- Address
- 1601 W Reynolds St, STE 203
Plant City, FL 33563 - Hours
- Monday–Friday, 8am–5pm
Participation is voluntary. You may withdraw at any time. Please consult with your doctor about all treatment options.